Treatment and prevention of HIV-1 infection. In appointing the drug as monotherapy to him quickly and almost always develop viral resistance, so it should always be assigned in combination with at least two other antiretroviral drugs.

Antiviral. Nevirapine is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) of HIV-1. Nevirapine is directly connected to the reverse transcriptase (ОT) and blocks RNA-and DNA-dependent DNA polymerase reaction, destroying the catalytic center of the enzyme.
The action of nevirapine is not competitive with respect to the nucleoside and nucleoside triphosphate. The drug does not block the reverse transcriptase of HIV-2 and DNA polymerase of eukaryotes (human DNA polymerase alpha, beta, gamma or delta).